Titlebook: Synthesis of Therapeutic Oligonucleotides; Satoshi Obika,Mitsuo Sekine Book 2018 Springer Nature Singapore Pte Ltd. 2018 Therapeutic oligo

CEDE

Acetaldehyde

同音

bifurcate

Synthesis and Therapeutic Applications of Oligonucleotides Containing 2′-,,4′-,-Ethylene- and 3′-,,4taining 3′-.,4′-.-propylene linkage can be incorporated into the third position of 2′,5′-oligoadenylate (2-5A) to maintain biological activities with nuclease resistance. This modified 2-5A with 3′-.,4′-.-propylene adenosine could be useful for novel anti-cancer and anti-viral reagents as an RNase L

針葉類的樹

RNA Bioisosteres: Chemistry and Properties of 4′-thioRNA and 4′-selenoRNAd nuclease resistance, as well as biocompatibility with natural RNA, and was used effectively as a chemically modified siRNA and for isolation of 4′-thioRNA aptamers. Current progress in the development of a new RNA bioisostere 4′-selenoRNA, which contains a selenium atom, is also described.

cajole

Book 2018esh ideas in nucleic acid chemistry that may ultimately lead to novel concepts and techniques and the discovery of more effective nucleic acid drugs. The book will be of high value for both established researchers in the field and students intending to specialize in nucleic acid chemistry research.

貧窮地活

osteocytes

otics scenarios. To demonstrate the utility of the causal models obtained from real-world datasets, we present a comparison between causal and non-causal prediction approaches. Our results show that the causal model correctly captures the underlying interactions of the considered scenarios and impro

ABASH