Titlebook: Orexin and Sleep; Molecular, Functiona Takeshi Sakurai,S.R. Pandi-Perumal,Jaime M. Monti Book 2015 Springer International Publishing Switze

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Birendra Nath Mallick,Mudasir Ahmad Khanday,Abhishek Singh

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Sara Lena Weinhold,Robert G?der,Paul Christian Baier

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and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular..978-3-319-35220-6978-3-319-23078-8

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Modulation of Thalamocortical Pathways by Orexins,Modern research on sleep-wake cycle and arousal is based on the ascending reticular arousal system (ARAS), described in the 1940s by Moruzzi and Magoun. This system is located in the upper brainstem and separates in two branches, one innervating the thalamus and the other the orexin and cholinergic nuclei of the basal forebrain.

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