Titlebook: Immersive Education; Designing for Learni Paula MacDowell,Jennifer Lock Book 2022 The Editor(s) (if applicable) and The Author(s), under ex

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cleosomes (the potential Targets). We describe key optimization steps and controls to generate robust binding data. Further, we compare the utility of histone peptide and nucleosome substrates in CAP studies, outlining important considerations in experimental design and data interpretation.