Titlebook: DNA Vaccines; W. Mark Saltzman,Hong Shen,Janet L. Brandsma Book 2006 Humana Press 2006 Antigen.T cell.autoimmunity.cell.molecular biology.

虛構(gòu)的東西

In Vitro Assay of Immunostimulatory Activities of Plasmid Vectorsand trigger a broad range of pro-inflammatory responses. Because this stimulation results from common sequence motifs, the activity of a plasmid vector can be assessed by the in vitro assay of a limited number of responses, including proliferation of B cells as well as production of cytokines by macrophages or dendritic cells.

引起痛苦

Identification of Compartments Involved in Mammalian Subcellular Trafficking Pathways by Indirect Immunofluorescence. Together with labeled delivery vectors and/or plasmid DNA, these methods can aid in the understanding of the trafficking pathways involved in DNA delivery, and contribute to the rational design of more efficient delivery vectors.

進(jìn)入

Adjuvant Properties of CpG Oligonucleotides in Primatess indicate that CpG oligonucleotides (ODN) are well tolerated and improve the immune response to microbial vaccines. This work examines the progress in utilizing CpG ODN as adjuvants in conventional and DNA vaccines.

Dislocation

Aadil Gani Ganie,Samad Dadvandipours the most commonly used vehicle formulations use materials selected for their general chemical inertness. This chapter describes methods for overcoming this, enabling encapsulation of DNA within degradable microspheres made of a commonly used biomaterial and then covalently conjugating ligands to the surface of these microspheres.

VEST

Abdulsadek Hassan,Mohammed Angawijection of these complexes efficiently primed long-lasting, specific CD8. T-cell immunity of high magnitude. This chapter describes a novel strategy to codeliver complexes of cationic/antigenic peptides bound to antigen-encoding plasmid DNA vaccines in a way that enhances the immunogenicity of both components for T cells.

BAIL

投射

抱狗不敢前

Surface-Modified Biodegradable Microspheres for DNA Vaccine Deliverys the most commonly used vehicle formulations use materials selected for their general chemical inertness. This chapter describes methods for overcoming this, enabling encapsulation of DNA within degradable microspheres made of a commonly used biomaterial and then covalently conjugating ligands to the surface of these microspheres.