Titlebook: DNA Vaccines; W. Mark Saltzman,Hong Shen,Janet L. Brandsma Book 2006 Humana Press 2006 Antigen.T cell.autoimmunity.cell.molecular biology.

裝入膠囊

繞著哥哥問

Complexes of DNA Vaccines With Cationic, Antigenic Peptides Are Potent, Polyvalent CD8+ T-Cell-Stimuity. We developed a novel vaccination strategy that used synthetic, cationic (positively charged), and antigenic peptides complexed to negatively charged nucleic acids: antigenic, major histocompatibility complex-class I-binding epitopes fused with a cationic sequence derived from the HIV tat protei

檢查

微粒

Modifying Professional Antigen-Presenting Cells to Enhance DNA Vaccine Potencyssional antigen-presenting cells (APCs), such as dendritic cells (DCs) play important roles in generating humoral and cell-mediated antigen-specific immune responses by DNA vaccination. Continuing progress in our understanding of how professional APCs uptake DNA, process and present the antigens enc

有節(jié)制

Replicase-Based DNA Vaccines for Allergy Treatmentnd low stability. At ultralow doses, these alphavirus-derived vectors elicit cellular as well as humoral immune responses. Additionally, replicase-based vectors induce “self-removal” of the vaccine via apoptosis of transfected cells. This chapter describes the construction of a replicon-based DNA va

Paradox

grovel

Dissonance

A簡潔的

固執(zhí)點好

Boris Kryzhanovsky,Vladimir Kryzhanovsky-encoding sequences cloned under heterologous promoter control are delivered by techniques that lead in vivo to antigen expression in transfected cells. DNA vaccination efficiently primes both humoral and cellular immune responses. We developed a novel expression system for DNA vaccines in which a f