Titlebook: DNA Vaccines; W. Mark Saltzman,Hong Shen,Janet L. Brandsma Book 2006 Humana Press 2006 Antigen.T cell.autoimmunity.cell.molecular biology.

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Aadil Gani Ganie,Samad Dadvandipourhancing DNA vaccines. This approach requires no additional development, and with an expanding market and willingness from jet injector manufacturers to produce prefilled syringes, the technique should become feasible for larger phase II/phase III trials.

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Boris Kovalerchuk,Kawa Nazemi,Ebad Banissiegies to increase the numbers of antigen-expressing DCs, strategies to enhance MHC class I and/or II presentation of the encoded antigen and strategies to prolong the life of antigen-expressing DCs to enhance DNA vaccine potency. We will also discuss the methodology involved in DNA vaccine developme

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Book 2006tion of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consi

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Alan Bundy,Kwabena Nuamah,Christopher Lucasmunofluorescence. Together with labeled delivery vectors and/or plasmid DNA, these methods can aid in the understanding of the trafficking pathways involved in DNA delivery, and contribute to the rational design of more efficient delivery vectors.

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Vaccination With Messenger RNAng evaluated in human clinical trials: (1) in vitro mRNA-transfection of dendritic cells to be adoptively transferred and (2) direct injection of globin-stabilized mRNA. This chapter describes the production of mRNA and the preparation of the two types of mRNA-based vaccines tested in humans.