Titlebook: Comprehensive Clinical Approach to Diabetes During Pregnancy; Dimitrios G. Goulis Book 2022 The Editor(s) (if applicable) and The Author(s

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Fetal Origin of Adult Disease: The Case of GDM and at birth, recent studies have linked GDM to risk for long-term disease in offspring, including impaired glucose tolerance and obesity. Investigations of the mechanisms by which GDM may “program” the exposed offspring to a higher risk of cardiometabolic disease later in life have suggested epige

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Medical Monitoring of Preexisting DM and GDMted complications and improves pregnancy outcomes. A multidisciplinary therapeutic approach that includes lifestyle modification (nutrition therapy, exercise, body weight control) and pharmacological treatment, in cases that it is necessary, is recommended. The therapeutic goal of DM treatment durin

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Obstetrical Monitoringes. In particular, an association of preexisting diabetes with increased congenital defects and stillbirth rates has been identified. In contrast, poor glycemic control, even in gestational diabetes mellitus, has been correlated with increased risk for macrosomia and shoulder dystocia during deliver

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Oral Anti-Hyperglycemic Agentshe mother and the fetus, as insulin does not cross the placenta. However, oral anti-hyperglycemic agents, including metformin and sulfonylureas, have been tried and are used in women with GDM in everyday practice worldwide, though the official Food and Drug Administration (FDA) license is still miss

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