Titlebook: Cellular Ca2+ Regulation; Douglas R. Pfeiffer,Jeanie B. McMillin,Steve Littl Book 1988 The Editor(s) (if applicable) and The Author(s), un

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Alkylating Toxins and the Liver Plasma Membrane Calcium Pump/Calcium ATPases attracted much interest (Trump and Berezesky, 1984; Schanne et al., 1979; Jewell et al., 1982; Lowrey et al., 1981; Bellomo and Orrenius, 1985). Clearly, many cellular processes are regulated or influenced by the cytosolic free calcium concentration, which in turn is controlled by calcium transpor

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Role of ATP and Na+ in the Regulation of Cytosolic Free Calcium in Kidney Cells in the endoplasmic reticulum. Fig. 1 shows the various ATP-dependent pumps and antiporters involved in the control of Ca.. and Na.. (In this figure, the plasmalemmal Na.-Ca. antiporter is conventionally assumed to operate in the forward mode i.e. Ca. efflux energized by Na. influx). Since Ca. trans

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Role of Guanine Nucleotide Regulatory Proteins and Inositol Phosphates in the Hormone Induced Mobilif such agonists are norepinephrine and epinephrine acting via α.-adrenergic receptors, vasopressin acting on V. receptors, ATP and ADP acting on P. purinergic receptors and angiotensin II. Each agonist, after binding to its specific cell surface receptor, provokes the hydrolysis of PI 4,5-P. by a ph

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Operatives ProduktionsmanagementThe hepatic microsomal Ca. sequestering system is analogous to that of sarcoplasmic reticulum and fulfills a similar role to it; namely, regulation of cytoplasmic Ca. concentration. It does so by taking up Ca. in an ATP dependent manner and releases it by either the reversal of the uptake process and/or by a different, unknown mechanism.