Titlebook: Store-Operated Ca2? Entry (SOCE) Pathways; Emerging Signaling C Klaus Groschner,Wolfgang F. Graier,Christoph Roman Book 2017Latest edition

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The STIM-Orai Pathway: Orai, the Pore-Forming Subunit of the CRAC Channeltudies that implicated Orai as part of the store-operated Ca. entry pathway and as the CRAC channel pore subunit, and finally examines ongoing work that is providing insights into CRAC channel structure and gating.

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The STIM-Orai Pathway: STIM-Orai Structures: Isolated and in Complexis for Orai channel activity. This chapter focuses on the available high-resolution structural details of STIM and Orai proteins with respect to the regulation of store-operated Ca. entry (SOCE). Solution structures of the Ca.-sensing domains of STIM1 and STIM2 are reviewed in detail, crystal struct

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The STIM-Orai Pathway: Orai, the Pore-Forming Subunit of the CRAC Channelat Orai is the pore subunit of the CRAC channel. It begins by reviewing briefly the defining characteristics of the CRAC channel, then discusses the studies that implicated Orai as part of the store-operated Ca. entry pathway and as the CRAC channel pore subunit, and finally examines ongoing work th

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