Titlebook: Stem Cell Technologies in Neuroscience; Amit K. Srivastava,Evan Y. Snyder,Yang D. Teng Book 2017 Springer Science+Business Media LLC 2017

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Reprogramming of Mouse Fibroblasts to Induced Oligodendrocyte Progenitor Cells,eurological diseases. However, direct access to oligodendrocyte progenitor cells has been challenging. Recently, cellular reprogramming technologies have demonstrated the ability to directly convert one cell type to another. This chapter describes the methods for the generation of induced oligodendr

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Development of Mouse Cell-Based In Vitro Blood-Brain Barrier Models,, handling and cultivating brain microvascular endothelial cells (BMEC) outside their natural environment is still a challenge. One of the strategies to get a stable BMEC culture is to generate an immortalized in vitro BBB model. This chapter describes how to isolate and immortalize mouse BMEC. A st

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Microfluidic Device for Studying Traumatic Brain Injury,ability in children and young adults. Studies show that axonal pathology and degeneration can cause significant functional impairment and can precede, and sometimes cause, neuronal death in several neurological disorders including TBI, creating a compelling need to understand the mechanisms of axon

閃光東本

Multimodal Neural Stem Cell Research Protocols for Experimental Spinal Cord Injuries,refore, the capability to perform reliable derivation, effective expansion, and long-term maintenance of primordial and uncommitted NSCs in vitro is essential for growing the capacities of stem cell biology and regenerative medicine. In this chapter, we systematically summarized a set of protocols a

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Real-Time Dual MRI for Predicting and Subsequent Validation of Intra-Arterial Stem Cell Delivery toTranslation of stem cell therapy is contingent upon overcoming the challenge of effective cell delivery to the human brain, which has a volume of ~1000 times larger than that of the mouse. Intra-arterial (IA) injection can achieve a broad, global, but if needed also spatially targeted biodistributio

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