Titlebook: Somatic Cell Nuclear Transfer; Peter Sutovsky Book 2007 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spring

Amnesty

Nuclear Remodeling and Nuclear Reprogramming for Making Transgenic Pigs by Nuclear Transfer,elopment of improved procedures for performing nuclear transfer and cloning. In some cases it appears that the gene(s) are reprogrammed, while in other cases there appears to be little effect on gene expression. Not only does the pattern of gene expression need to be reprogrammed, but other structur

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煩憂

Centrosome Inheritance after Fertilization and Nuclear Transfer in Mammals,roteins that typically surround a pair of perpendicularly oriented cylindrical centrioles. Centrosome matrix is therefore oftentimes referred to as pericentriolar material (PCM). Through their microtubule organizing functions centrosomes are also crucial for transport and distribution of cell organe

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Developmental, Behavioral, and Physiological Phenotype of Cloned Mice,y feasible, prenatal and perinatal mortality is high and live cloned offspring have had health problems. This chapter summarizes the health consequences of cloning in mice and discusses possible mechanisms through which these conditions may arise. These studies have further significance as other ass

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FEIGN

Somatic Cell Nuclear Transfer (SCNT) in Mammals,CNT) is still disappointingly low. Only about 3–5% of reconstructed embryos develop to term, and it is also evident that even if some clones are born, they are not necessarily fully developed and healthy. Embryonic and neonatal abnormalities of cloned offspring are probably a result of incorrect or

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Cloning Cattle, the impact of epigenetic and genetic differences between embryonic, germ, and somatic donor cell types on cloning efficiency. Lastly, we discuss adult phenotypes and fitness of cloned cattle and their offspring and illustrate some of the more imminent commercial cattle cloning applications.