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Titlebook: Somatic Cell Nuclear Transfer; Peter Sutovsky Book 2007 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spring

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發(fā)表于 2025-3-21 16:37:20 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Somatic Cell Nuclear Transfer
編輯Peter Sutovsky
視頻videohttp://file.papertrans.cn/872/871841/871841.mp4
概述Provides timely, refreshing new angle on the cellular and molecular events of somatic cell nuclear transfer (SCNT), one of the most exciting new biotechnologies of the last decade.Written by a unique
圖書封面Titlebook: Somatic Cell Nuclear Transfer;  Peter Sutovsky Book 2007 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spring
描述When I was first approached to edit the present volume, I was somewhat reluc- tant to undertake this humbling task because most of my own scientific expertise is derived fi‘om studies of mammalian fertilization rather than somatic cell nuclear transfer (SCNT). However, in the last ten years, I was very fortunate to train, col- laborate, and communicate with a number of distinguished "doners," many of whom kindly agreed to contribute to the present volume. This experience made me appre- ciate that the understanding of cellular and molecular events during and after SCNT is deeply rooted in our knowledge of fertilization of mammalian ovum by the speramatozoon, to which I prefer to refer to as "natural fertilization," not to say that SCNT should be regarded as "unnatural fertilization". Unique cellular events aris- ing from SCNT have no parallel in natural fertilization and early pre-implantation development. The list includes the requirement of donor cell-nuclear remodeling, disposal of donor cell organelles, the possibility of heteroplasmy (i. e. , presence of mixed mitochondrial genomes) and altered mode of oocyte activation. Thanks to seminal contributions of my distinguished colle
出版日期Book 2007
關(guān)鍵詞Activation; DNA; Mammalia; Organelle; Regulation; development; phenotype
版次1
doihttps://doi.org/10.1007/978-0-387-37754-4
isbn_softcover978-1-4899-8745-7
isbn_ebook978-0-387-37754-4
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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沙發(fā)
發(fā)表于 2025-3-21 23:51:17 | 只看該作者
http://image.papertrans.cn/s/image/871841.jpg
板凳
發(fā)表于 2025-3-22 01:27:06 | 只看該作者
地板
發(fā)表于 2025-3-22 07:42:44 | 只看該作者
Peter SutovskyProvides timely, refreshing new angle on the cellular and molecular events of somatic cell nuclear transfer (SCNT), one of the most exciting new biotechnologies of the last decade.Written by a unique
5#
發(fā)表于 2025-3-22 12:33:45 | 只看該作者
6#
發(fā)表于 2025-3-22 16:49:43 | 只看該作者
Nuclear Remodeling and Nuclear Reprogramming for Making Transgenic Pigs by Nuclear Transfer,icient process. However, even with the current low efficiencies this technique has proved very valuable for the production of animals that might be useful for tissue or organ transplantation to humans.
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發(fā)表于 2025-3-22 21:08:14 | 只看該作者
Somatic Cell Nuclei in Cloning,at the somatic cell chromatin only infrequently manages the successful transition to a competent surrogate for gamete genomes. This review focuses on recent results revealing these limitations and how they might be overcome.
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發(fā)表于 2025-3-22 22:12:01 | 只看該作者
Developmental, Behavioral, and Physiological Phenotype of Cloned Mice,RT display aberrant phenotypes as well. At the moment, the long-term consequences of mammalian cloning remain poorly characterized. Data available thus far suggest that we should use this technology with great caution until numerous questions are addressed and answered.
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發(fā)表于 2025-3-23 03:07:02 | 只看該作者
Somatic Cell Nuclear Transfer (SCNT) in Mammals, role in the process of reprogramming has been attributed to the enucleated oocyte-cytoplast into which the somatic cell nucleus is transferred. In our chapter, we will discuss the methodological approaches used for the preparation of cytoplasts and their possible reprogramming activities.
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發(fā)表于 2025-3-23 06:29:50 | 只看該作者
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