Titlebook: Signal Transduction in the Cardiovascular System in Health and Disease; Ashok K. Srivastava,Madhu B. Anand-Srivastava Book 2008 Springer-V

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Methylglyoxal and Insulin Resistancetations are associated with increased cardiovascular risks. Currently, the causes and mechanisms of insulin resistance remain poorly understood. Methylglyoxal (MG) is a highly reactive metabolite of sugar. Increased MG levels and MG-related advanced glycation endproducts have been reported in differ

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Role of Growth Factor Receptor Transactivation in Vasoactive Peptide-Induced Signaling Pathways in Vsuch as hypertension, atherosclerosis, hypertrophy, and restenosis. These peptides elicit their biological effects through the activation of transmembrane guanine nucleotide-binding protein-coupled receptors (GPCRs). GPCR activation results in the stimulation of several signaling pathways including

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Identifying the Cellular and Molecular Events Associated with the Divergent Phenotypes of Cardiac Hy in the absence of cell division. This process is characterized as cardiac hypertrophy and the pattern of individual myocyte growth is directly influenced by the nature of the hemodynamic load. Cardiac hypertrophy can be classified as either physiological or pathological and their disparate phenotyp

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Therapeutic Angiogenesis and Vasculogenesis for Ischemic Diseaseeading cause of morbidity and mortality in the United States. Thus, one of the main goals in the treatment of myocardial ischemia is the development of effective therapy for angiogenesis. The first evidence we found is the demonstration of alleviation of myocardial ischemia and increased number of c

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