Titlebook: Signal Transduction in the Cardiovascular System in Health and Disease; Ashok K. Srivastava,Madhu B. Anand-Srivastava Book 2008 Springer-V

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Signal Transduction in the Cardiovascular System in Health and Disease

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Angiotensin II Signaling: Cell Growth and Apoptosisgh the recent introduction of transgenic animals has proven valuable in assessing the contribution of specific pathways in the regulation of growth and apoptosis, more information is required on the interplay between these pathways and mediators of growth and apoptosis.

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Thioredoxin Signaling in the Ischemic Hearting these findings, transgenic mouse hearts overexpressing Trx-1 were resistant to ischemic reperfusion injury as compared to the hearts from wild-type mice. Thus, it appears that thioredoxin plays a crucial role in cardioprotection induced by preconditioning.

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Implication of G-proteins in Cardiovascular Diseasee/cAMP and phospholipase C (PLC)/phosphatidylinositol turnover (PI) which are implicated in the modulation of a variety of physiological functions such as platelet functions, including platelet aggregation, secretion, and clot formation, and cardiovascular functions, including arterial tone and reac

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The Role of the Beta-Adrenergic Signal Transduction Pathway in Myocardial Protectionon pathway can, however, also elicit protective responses in the myocardium. Activation of the beta-adrenergic signal transduction pathway participates in the protective effect of ischemic preconditioning, and administration of catecholaminergic agents such as isoproterenol and noradrenaline can eli

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