| 書目名稱 | Selenium | | 副標(biāo)題 | Its Molecular Biolog | | 編輯 | Dolph L. Hatfield,Marla J. Berry,Vadim N. Gladyshe | | 視頻video | http://file.papertrans.cn/865/864355/864355.mp4 | | 概述 | Features the many new discoveries have occurred since the 1st edition on Selenium was published in 2001.New investigators who have made important contributions to the field have been added as chapter | | 圖書封面 |  | | 描述 | The discovery of selenoproteins in 1973 was the starting point for today‘s flourishing selenium field [1,2]. It provided evidence that selenium had biochemical functions that could account for its nutritional effects [3,4]. Further, it opened the selenium field to investigation by the methods of biochemistry, which led to the identification of several more selenoproteins and showed that selenocysteine was the form of the element in animal selenoproteins and in most bacterial ones. Although noteworthy efforts were made to uncover the mechanism of selenocysteine and selenoprotein synthesis using biochemical methods, the problem yielded only when attacked with the methods of molecular biology [5,6]. The bacterial mechanism was characterized first; characterization of the animal mechanism is a work in progress. It is interesting to note that the only genes that are devoted to selenium metabolism are those that support selenoprotein synthesis and selenocysteine catabolism. Consequently, it seems likely that competition for selenium between selenoprotein synthesis and the production of selenium excretory metabolites [7] controls who- body selenium homeostasis. The physiological functions | | 出版日期 | Book 20062nd edition | | 關(guān)鍵詞 | AIDS; Diabetes; Evolution; HIV; Proteomics; RNA; Regulation; biosynthesis; cancer; genes; metabolism; molecular | | 版次 | 2 | | doi | https://doi.org/10.1007/0-387-33827-6 | | isbn_ebook | 978-0-387-33827-9 | | copyright | Springer-Verlag US 2006 |
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