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Titlebook: Regulatory Networks in Stem Cells; Vinagolu K. Rajasekhar,Mohan C. Vemuri Book 2009 Humana Press 2009 DNA.Expression.Telomere.anatomy.cell

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發(fā)表于 2025-3-21 17:52:19 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Regulatory Networks in Stem Cells
編輯Vinagolu K. Rajasekhar,Mohan C. Vemuri
視頻videohttp://file.papertrans.cn/826/825747/825747.mp4
概述Incorporates all essential and relevant information in the study of stem cells.Excellently presented data by leading experts in the field of stem cells.Includes supplementary material:
叢書(shū)名稱Stem Cell Biology and Regenerative Medicine
圖書(shū)封面Titlebook: Regulatory Networks in Stem Cells; Vinagolu K. Rajasekhar,Mohan C. Vemuri Book 2009 Humana Press 2009 DNA.Expression.Telomere.anatomy.cell
描述Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues. The characteristics of stem cells that distinguish them from other cells have been the fascinating subjects of stem cell research. The important properties of stem cells, such as ma- tenance of quiescence, self-renewal capacity, and differentiation potential, have propelled this exciting ?eld and presently form a common theme of research in developmental biology and medicine. The derivation of pluripotent embryonic stem cells, the prospective identi?cation of multipotent adult stem cells, and, more recently, the induced pluripotent stem cells (popularly called iPS) are important milestones in the arena of stem cell biology. Complex networks of transcription factors, different signaling molecules, and the interaction of genetic and epi- netic events constantly modulate stem cell behavior to evoke programming and reprogramming processes in normal tissue homeostasis during development. In any given cellular scenario, the regulatory networks can pose considerable complexity and yet exert an order
出版日期Book 2009
關(guān)鍵詞DNA; Expression; Telomere; anatomy; cells; developmental biology; endothelium; gene expression; genes; geneti
版次1
doihttps://doi.org/10.1007/978-1-60327-227-8
isbn_softcover978-1-4939-5696-8
isbn_ebook978-1-60327-227-8Series ISSN 2196-8985 Series E-ISSN 2196-8993
issn_series 2196-8985
copyrightHumana Press 2009
The information of publication is updating

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Asymmetric Behavior in Stem Cellscell divisions result in one daughter cell that is similar to the parent cell and, hence, necessarily allows for self-renewal of the stem cell phenotype, whereas the other daughter cell is a differentiated or committed cell type. In this chapter we will discuss the role of asymmetry in stem cell div
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Maintenance of Embryonic Stem Cell Pluripotency by Nanog-Mediated Dedifferentiation of Committed Meshe molecular and cellular mechanisms underlying ES cell pluripotency are, however, poorly understood. Here, we characterize a population of early mesoderm-committed (EM) progenitors that is generated from mouse ES cells by bone morphogenetic protein (BMP) stimulation. We further show that EM progeni
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發(fā)表于 2025-3-22 10:09:49 | 只看該作者
Human Embryonic Stem Cells and Germ Cell Developmenthree primary germ layers. Evidence shows, however, that the cells of the ICM and derived ESCs are not identical. Expression of early germ cell–specific markers in undifferentiated ESCs and the ability of ESCs to differentiate into functional germ cells in vitro suggest that early germ cells and ESCs
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發(fā)表于 2025-3-22 16:17:47 | 只看該作者
Genomic Stability in Stem Cellsts to genomic integrity. Reactive oxygen species, the most significant mutagens in stem cells, when elevated, activate the protective mechanisms blocking self-renewal and at the same time serve as a signal stimulating stem cell differentiation. Based on studies performed primarily on hematopoietic s
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Use of Zebrafish to Dissect Gene Programs Regulating Hematopoietic Stem Cellsw to maintain their own population so that the blood system always has the capacity to be reconstituted. This balance of HSCs producing more HSCs as well as differentiated blood cells is regulated by several extrinsic pathways. The . pathway has been shown to have a role in regulating embryonic stem
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