Titlebook: Regulatory Networks in Stem Cells; Vinagolu K. Rajasekhar,Mohan C. Vemuri Book 2009 Humana Press 2009 DNA.Expression.Telomere.anatomy.cell

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Extrinsic and Intrinsic Control of Germline Stem Cell Regulation in the , Ovary also one of the best defined ones. Due to the availability of powerful genetic tools and a large number of mutants, much progress has been made in understanding the molecular mechanisms underlying intrinsic and extrinsic controls of GSC regulation within the past decade. Since several excellent rev

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Microenvironmental Regulation of Adult Mesenchymal Stem CellsMSCs). The focus is on microenvironmental cues that represent a concert of signals coming from the niche in which the MSC finds itself. These signals are generated by contact with surrounding cells, by soluble factors that can be autocrine, paracrine, or endocrine in nature, and by the extracellular

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The Niche Regulation of Hematopoietic Stem Cellsed. Furthermore, the niche’s involvement in cancer stem regulation, tumor invasion, and metastasis, and novel therapeutic approaches used in association with the cancer stem cell niche are also described.

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Microenvironmental Regulation of Adult Mesenchymal Stem Cellssignals work together in intricate harmony to regulate the regenerative abilities of MSCs. By learning more about the mechanisms of action, specificities and interactions of each member of this environmental orchestra, it will be possible to manipulate MSCs for therapeutic applications to diseases and injuries.

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