Titlebook: Redox-Active Therapeutics; Ines Batini?-Haberle,Júlio S. Rebou?as,Ivan Spasoj Book 2016 Springer International Publishing Switzerland 2016

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Superoxide and the Superoxide Dismutases: An Introduction by Irwin Fridovich,nt reduction by pairs of spin-opposed electrons. The reactivity of superoxide, and of its conjugate acid the hydroperoxyl radical, threatens aerobic life. Defenses are essential and these are provided by superoxide dismutases (SODs) that efficiently catalyze the conversion of superoxide into oxygen

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The Discovery of Superoxide Dismutase and Its Role in Redox Biology,ed in biological systems? How was it toxic? Were there positive contributions associated with superoxide production? Was it involved in a delicate redox balance? Decades later these questions are still being clarified.

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