Titlebook: Rab GTPases; Methods and Protocol Guangpu Li,Nava Segev Book 2021Latest edition The Editor(s) (if applicable) and The Author(s), under excl

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https://doi.org/10.1007/978-1-0716-1346-7Alzheimer’s; clathrin-independent endosomal trafficking; pull-down assays; invadopodia formation; confoc

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Generating , Conditional Knockout Mice,RAB6 GTPase is the most abundant Golgi-associated RAB protein and regulates several transport steps at the level of this organelle. Homozygous . knockout (k/o) is embryonic lethal in mouse. To study RAB6 function in cell lineages and tissues, we thus generated various conditional . knockout (k/o) mice using the Cre/lox system.