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Titlebook: Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery; Gus R. Rosania,Greg M. Thurber Book 2021 Springer Science+Bus

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發(fā)表于 2025-3-21 18:46:19 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery
編輯Gus R. Rosania,Greg M. Thurber
視頻videohttp://file.papertrans.cn/781/780788/780788.mp4
概述Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Features information that applies to a wide array of research areas
叢書名稱Methods in Pharmacology and Toxicology
圖書封面Titlebook: Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery; Gus R. Rosania,Greg M. Thurber Book 2021 Springer Science+Bus
描述This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the?.Methods in Pharmacology and Toxicology.?series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from read
出版日期Book 2021
關(guān)鍵詞Pharmacokinetics; Drug development; Small molecule pharmacology; Biologics; Macromolecule transport; Nano
版次1
doihttps://doi.org/10.1007/978-1-0716-1250-7
isbn_softcover978-1-0716-1252-1
isbn_ebook978-1-0716-1250-7Series ISSN 1557-2153 Series E-ISSN 1940-6053
issn_series 1557-2153
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2021
The information of publication is updating

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d plexus secreting cerebrospinal fluid (CSF) into the ventricles and the arachnoid epithelium forming the middle layer of the meninges on the brain surface. There are three key barrier features at each site that control the composition of brain fluids and regulate CNS drug permeation: (i) physical b
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Kyoung Ah Min,Gus R. Rosaniad plexus secreting cerebrospinal fluid (CSF) into the ventricles and the arachnoid epithelium forming the middle layer of the meninges on the brain surface. There are three key barrier features at each site that control the composition of brain fluids and regulate CNS drug permeation: (i) physical b
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Mikhail D. Murashovociated problems. This interest has arisen not only because of the increasing number of drug dependents but also because of the psychological and sociological causes and consequences of drug abuse. It has become increasingly clear that drug dependencies—such as alcoholism—originate not only in the p
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Richard W. Horobin,Juan C. Stockertaction between a living organism and a drug, characte- rized by behavioural and other responses that always include a com- pulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance mayor may
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