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Titlebook: Osteoporosis in Older Persons; Pathophysiology and Gustavo Duque,Douglas P. Kiel Book 2009 Springer-Verlag London 2009 Fractures.Osteoporo

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發(fā)表于 2025-3-21 19:28:47 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Osteoporosis in Older Persons
副標題Pathophysiology and
編輯Gustavo Duque,Douglas P. Kiel
視頻videohttp://file.papertrans.cn/705/704939/704939.mp4
概述Describes the epidemiology of osteoporotic fractures and their impact on health care costs.Integrates the subject of falls with the one on fractures - widely neglected by most of the textbooks on oste
圖書封面Titlebook: Osteoporosis in Older Persons; Pathophysiology and  Gustavo Duque,Douglas P. Kiel Book 2009 Springer-Verlag London 2009 Fractures.Osteoporo
描述Although osteoporosis has been de? ned as “a metabolic bone disease characterized by low bone mass and microarchitectural deterioration of bone tissue leading to enhanced bone fragility and a consequent increase in fracture risk,” it is not clear that osteoporosis represents a single disease as much as a similar response of bone to different pathophysiologies. In the 1940s Fuller Albright and colleagues recognized “osteoporosis of old age” and distinguished it from osteoporosis associated with the postme- pausal state, as well as from osteoporosis from disuse, osteoporosis from malnutrition, and other forms of osteoporosis. He nevertheless pointed out that it was unclear how much of osteoporosis is due to old age per se, in view of the fact that “in many cases osteoporosis of disuse, of malnutrition, of the postmenopausal state and of senility are inseparably superimposed. ” In this volume, Duque and Kiel have gathered an international panel of experts to highlight the unique features of senile osteoporosis and cons- eration of this disease spans the very basic through the clinical and the epidemiologic. As an organ which harbors stem cells, bone may clearly in? uence not only its
出版日期Book 2009
關(guān)鍵詞Fractures; Osteoporosis; aging; geriatrics; sex; steroids
版次1
doihttps://doi.org/10.1007/978-1-84628-697-1
isbn_softcover978-1-84882-924-4
isbn_ebook978-1-84628-697-1
copyrightSpringer-Verlag London 2009
The information of publication is updating

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發(fā)表于 2025-3-21 23:44:13 | 只看該作者
Sex Steroids and Aging Bone,es. In this chapter, the evidence supporting a role for sex steroids in maintaining the skeleton into old age is reviewed. The focus is on both estrogen and testosterone in men and women from an epi-demiologic perspective.
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Animal Models for Senile Osteoporosis,Among those mice, some are considered to be potent models for understanding the pathophysiology of senile osteoporosis in humans. Here, available models for the study of senile osteoporosis, and mouse models in particular, are introduced and discussed.
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發(fā)表于 2025-3-22 19:14:38 | 只看該作者
models minimises inter-individual differences, allows specific pathological changes to be examined, and facilitates collection of tissue samples. Thus, mechanistic research and identification of biomarkers are possible. Various animal models manifesting specific pathological lesions can be used to i
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Jeffrey M. Gimble MD, PhD,Z. Elizabeth Floyd,Moustapha Kassem MD, PhD, DSc,Mark E. Nuttall PhDoteome in different ways. Moderate-intensity exercise results in increased glomerular filtration, meaning that medium-sized proteins are excreted in higher amounts, while high-intensity exercise of short duration also increases the excretion of low molecular weight proteins as a result of tubular dy
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E. Paul Cherniack MD,Bruce R. Troen MDoteome in different ways. Moderate-intensity exercise results in increased glomerular filtration, meaning that medium-sized proteins are excreted in higher amounts, while high-intensity exercise of short duration also increases the excretion of low molecular weight proteins as a result of tubular dy
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發(fā)表于 2025-3-23 09:18:49 | 只看該作者
Jane A. Cauleymodels minimises inter-individual differences, allows specific pathological changes to be examined, and facilitates collection of tissue samples. Thus, mechanistic research and identification of biomarkers are possible. Various animal models manifesting specific pathological lesions can be used to i
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