| 書目名稱 | Oncolytic Viruses | | 副標(biāo)題 | Methods and Protocol | | 編輯 | David H. Kirn,Ta-Chiang Liu,Stephen H. Thorne | | 視頻video | http://file.papertrans.cn/702/701394/701394.mp4 | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | .Since the first report of an engineered oncolytic virus, there has been a continuing and steady increase of interest in the field, and while bench research remains vital for the translation of research in this field, its success depends on breakthroughs in clinical studies. .Oncolytic Viruses: Methods and Protocols. describes the construction and purification of capsid-modified adenoviruses as well as oncolytic adenoviruses, presents protocols for many individual virus species including engineering and preparation of oncolytic HSV, propagation, purification, and .in vivo. testing of oncolytic VSV, details properties of oncolytic reovirus and NDV, and describes the generation and testing of next generation of oncolytic vaccinia virus. As the host immune system plays a critical role in determining efficacy of oncolytic viruses, two chapters are devoted to the study of immune response. Recent advances in stem cell research have led the field in two distinct directions: the use of stem cells as carrier vehicles for oncolytic viruses and the targeting of cancer stem cells. As such, the volume describes the use of explant tissue samples from patients to potentially provide useful inform | | 出版日期 | Book 2012 | | 關(guān)鍵詞 | Newcastle disease virus; Vaccinia virus; capsid-modified adenovirus; oncology; oncolytic reovirus; stem c | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-61779-340-0 | | isbn_softcover | 978-1-4939-5812-2 | | isbn_ebook | 978-1-61779-340-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC 2012 |
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