Titlebook: Neuroimmune Diseases; From Cells to the Li Hiroshi Mitoma,Mario Manto Book 20191st edition Springer Nature Switzerland AG 2019 neuroimmunol

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Genetic Factors in Neuroimmune Diseasesst majority of neuroimmune disorders, suggesting that dysfunctions in the antigen presentation process likely play a pivotal role in their pathophysiology. However, further studies will be necessary to fully describe the multifactorial nature of such complex diseases and discover all the molecular p

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Paraneoplastic Neurological Syndromesic T cells. PNS with onconeural antibodies respond poorly to immunotherapy, with the exception of anti-Ma2 PNS. A second group of antibodies against synaptic and cell surface proteins occur in well-defined neurological syndromes, which are not always PNS and may appear in younger patients without ca

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Multiple Sclerosishe onset, termed primary progressive MS (PPMS)..MS is assumed to be an autoimmune disease but this is not yet proven. In addition to major effects of human leukocyte antigen (HLA) class II genes (such as .), genome-wide association studies have revealed many susceptibility genes for MS with modest e

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Neuromyelitis Optica Spectrum Disorderto treat multiple sclerosis, such as interferon beta and natalizumab, exacerbate NMO. Maintenance treatment options include prednisolone, mycophenylate, mitoxantrone, cyclophosphamide, azathioprine, rituximab, tocilizumab and eculizumab. The discoveries of AQP4-IgG and MOG-IgG have shown that NMO is

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Paulus S. Rommer,Michael Hecker,Tobias Zrzavy,Nina Boxberger,Uwe K. Zettl

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Samira Saadoun,Vincent T. W. Chang,Marios C. Papadopoulos

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tional success . (The Orphanage, Bayona 2007) to suggest that horror heroines can also be horror monsters: the monstrous mothers not only of horror theorist Barbara Creed (1993) but also as posited by Kinder as mentioned above. Horror and fantasy become specifically female constructs (since the trut

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