Titlebook: Neurodegenerative Diseases; Molecular and Cellul Gary Fiskum Book 1996 Springer Science+Business Media New York 1996 Alzheimer.Amino acid.C

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HIV-1 Coat Protein GP120 Induces Neuronal Injury to Cultured Dopamine Cellsr impairments.. Concomitant with this are CNS disturbances which can include various organic mental disorders.. These CNS disturbances may occur in the absence of opportunistic infections as well as in the absence of direct infection of neurons by HIV-1.. In fact, HIV-1 has only been demonstrated in

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Platelets as Peripheral Model of Glutamate-Related Excitotoxicity in Parkinson’s Diseases in Parkinson’s Disease (PD).. Defects in mitochondrial enzymes, which make dopaminergic cells more susceptible to oxidative stress, have been found not only in substantia nigra of PD patients., but also in their peripheral tissues.and blood platelets.. Recent studies also indicated that impaired m

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Glossy

Biology of APP and its Homologues derived from larger type I integral membrane glycoproteins, termed the amyloid precursor proteins (APP).. APP is a member of a family of homologous amyloid precursor-like proteins (APLPs), including APLP1. and APLP2.. APP, APLP1, and APLP2 show considerable homology in the N-terminal cysteine-rich

ineffectual

Lymphocyte Amyloid Precursor Protein mRNA Isoforms in Normal Aging and Alzheimer’s Diseasentain 770, 751 and 695 amino acids, respectively. The two longer forms of the molecule contain a Kunitz-type serine protease inhibitor domain (KPI). These longer isoforms (APP. and APP.) are the principal species found in non-neuronal cells whereas the shorter APP. is the major form in differentiate

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Mutations of Human Cu, Zn Superoxide Dismutase Expressed in Transgenic Mice Cause Motor Neuron Disea and have an unknown etiology.. However, about 10–15% of all ALS cases are inherited. An adultonset, autosomal dominantly inherited trait is the predominant form., although there is a rare, recessively inherited childhood-onset form of ALS in which survival can be quite long.. In 1991, a fraction of

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