Titlebook: Natural Products; Drug Discovery and T Lixin Zhang,Arnold L. Demain Book 2005 Humana Press 2005 cancer.drug.drug delivery.drug discovery.re

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Manipulating Microbial Metabolites for Drug Discovery and Productionral-product drug leads and therapeutically important drugs, can be increased by altering the function of the genes and enzymes that govern the production of these metabolites. In particular, the predictable relationship between the structure and function of the modular type of microbial polyketide s

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Case Studies in Natural-Product Optimizationluding the clinically important antitumor agents vinblastine and vincristine. Both classes of antitumor agents interfere with tubulin-microtubule dynamics through opposite modes of action. They are the most renowned natural products, have been successfully brought to market, and have also served as

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Arsenic Trioxide and Leukemiamon, naturally existing substance, is rarely found in its pure elemental state in nature. In addition to the organic arsenicals, there are three major inorganic arsenic forms: red arsenic (As.S.), yellow arsenic (As.S.), and white arsenic (As.O., ATO). Based on the basic TCM theory of “using poison

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