Titlebook: Nanotoxicity; Methods and Protocol Qunwei Zhang Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 Nanotoxicology

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Evaluation of Nrf2 with Exposure to Nanoparticles, in antioxidant and anti-inflammatory defence. It has been largely reported that oxidative stress is implicated in nanoparticle-induced toxicity with the involvement of Nrf2. Several basic methods for Nrf2 evaluation with exposure to nanoparticles are described in this chapter including real-time re

連系

Mortar

Mangle

,Methods to Quantify Nanomaterial Association with, and Distribution Across, the Blood–Brain Barrieraterial interaction with, and distribution across, it into brain tissue (parenchyma). Transport mechanisms across the BBB are presented, in relation to nanomaterial physicochemical properties. Measures and test substances to assess BBB integrity/disruption/permeation are introduced, along with how t

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剝削

Evaluation of Pulmonary Toxicity of Nanoparticles by Bronchoalveolar Lavage,s may be investigated by histopathological examination, immunostaining, bronchoalveolar lavage (BAL), and so on. BAL is a simple, fast, and inexpensive method that is commonly used to investigate the immune cells and acellular components in the lungs, which reflect the health state of the lungs. In

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Pulmonary Function Testing in Animals,anoparticles means that they are respirable and can penetrate deep into the lung when inhaled. Because of this, there is interest in assessing possible toxic effects of nanoparticles on the respiratory system. Measurement of respiratory mechanics and pulmonary function represents a sensitive way of

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Methods for Evaluation of Ovarian Granulosa Cells with Exposure to Nanoparticles,nduced toxicity of GCs by interfering with cell cycle. Some basic methods for evaluation of GCs with exposure to nanoparticles are described in this chapter including isolation of GCs, determination of apoptosis by immunofluorescence, and measurement of progesterone level by ELISA.