Titlebook: Microenvironments in the Lymphoid System; G. G. B. Klaus Book 1985 The Editor(s) (if applicable) and The Author(s), under exclusive licens

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Comparative Analysis of the Development of B Cells in Marginal Zones and Folliclesponses to T cell-independent type 2 (TI-2) antigens and recirculating cells in responses to T cell-dependent antigens (3). This paper describes observations which give insight into the development and maturation of the recirculating follicular (RF) B cells and marginal zone (MZ) B cells.

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Prospects for Understanding the Role of Lymphoid Microenvironments in B Cell Differentiation , e role of lymphoid tissue microenvironments, and in particular of germinal centers, in controlling the development and differentiation of functional B cell subsets. Gerry Klaus, in his introductory remarks in our abstract books, emphasized the fact that germinal centers seem rather an esoteric topic

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Pre-B Cells in Rat Bone Marrow: Identification, Surface Markers and Isolation B-lymphocyte stem cells (1). These cells carry the Thy-1 and W3/13 antigens (2, 3). Pre-B cells characterized by the presence of μ heavy chains in the cytoplasm (cμ) but not on the cell surface (sμ) have been described in mice (4), men (5) and rabbits (6) but not in rats, and appear to be the immed

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T Cell Markers on Pre-B Cells in the Ratre B cells [1]. The spleens of such mice were subsequently used for hybridisation with the SP2/0 fusion line. These fusions resulted in a panel of monoclonal antibodies reacting with determinants on rat lympho-haemopoietic cells. Based on data obtained in flow cytometry and immune peroxidase histolo

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Influence of the , Mutation on B Lymphocyte Development in Adult Micens, surface IgM and IgD [1, 2]. In the spleen at least three distinct populations of B cells can be identified on the basis of the relative concentrations of surface IgM and IgD [3]. One of these, carrying high IgD and low IgM concentrations, is absent in CBA/N mice, which are homozygous for the X-l

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In Vitro Growth and Differentiation of Rat B Cell Subpopulationsdistribution behaviour of their surface immunoglobulin (sIg). One of these subsets consists of medium-sized lymphocytes that form caps with anti-immunoglobulin antibodies. The other subset consists of small lymphocytes that do not form sIg-caps, but show rapid endocytosis in the cap configuration 1,

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Monoclonal Antibodies to Rat B Lymphocyte (Sub-)PopulationsAb’s binding to cell surface determinants of B lineage cells has been described (1). However, as yet almost no B lineage specific MAb’s have been described for the rat. Since this animal appears very appropiate for studies of early phases of B lymphocyte differentiation (2) as well as late phases, i