Titlebook: Mathematical Methods for Protein Structure Analysis and Design; Advanced Lectures Concettina Guerra,Sorin Istrail Conference proceedings 20

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Geometric Methods for Protein Structure Comparison,. As proteins fold in three dimensional space, assuming a variety of shapes, a careful characterization of their geometry is needed to study their function which is known to be related to the shape. Moreover, the comparison of protein structures is essential to infer evolutionary information.

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Prediction of Protein Secondary Structure at High Accuracy Using a Combination of Many Neural Netwoof 80% is obtained for three-state (helix, strand, coil) DSSP categories. Input to primary-layer neural networks includes sequence profiles, relative residue position, relative chain length, and amino-acid composition. Secondary structure predictions are made for three consecutive residues simultane

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Self-consistent Knowledge-Based Approach to Protein Design,sequence of amino acids of a naturally-occurring protein uniquely specifies its thermodynamically stable native structure. The protein folding challenge consists of predicting the native state of a protein from its sequence of amino acids, while in protein design one is concerned to identify the ami

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ded as comingofage. Pul- sars and accreting neutron stars have now been studied at every wavelength, from the initial radio observations, through optical, X-, and "{-ray, up to the very recent observations in the TeV region, while theorists have studied in some detail relevant physical processes bot

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