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Titlebook: Mathematical Methods for Protein Structure Analysis and Design; Advanced Lectures Concettina Guerra,Sorin Istrail Conference proceedings 20

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書(shū)目名稱Mathematical Methods for Protein Structure Analysis and Design
副標(biāo)題Advanced Lectures
編輯Concettina Guerra,Sorin Istrail
視頻videohttp://file.papertrans.cn/627/626247/626247.mp4
概述Includes supplementary material:
叢書(shū)名稱Lecture Notes in Computer Science
圖書(shū)封面Titlebook: Mathematical Methods for Protein Structure Analysis and Design; Advanced Lectures Concettina Guerra,Sorin Istrail Conference proceedings 20
描述The papers collected in this volume reproduce contributions by leading sch- arstoaninternationalschoolandworkshopwhichwasorganizedandheldwith thegoaloftakinga snapshotofadiscipline undertumultuous growth. Indeed, the area of protein folding, docking and alignment is developing in response to needs for a mix of heterogeneous expertise spanning biology, chemistry, mathematics, computer science, and statistics, among others. Some of the problems encountered in this area are not only important for the scienti?c challenges they pose, but also for the opportunities they disclose intermsofmedicalandindustrialexploitation. Atypicalexampleiso?eredby protein-drug interaction (docking), a problem posing daunting computational problems at the crossroads of geometry, physics and chemistry, and, at the same time, a problem with unimaginable implications for the pharmacopoeia of the future. The schoolfocused on problems posed by the study of the mechanisms - hind protein folding, and explored di?erent ways of attacking these problems under objective evaluations of the methods. Together with a relatively small core of consolidated knowledge and tools, important re?ections were brought to this e?or
出版日期Conference proceedings 2003
關(guān)鍵詞algorithms; calculus; computational biology; computational molecular biology; data analysis; genome; neura
版次1
doihttps://doi.org/10.1007/b11686
isbn_softcover978-3-540-40104-9
isbn_ebook978-3-540-44827-3Series ISSN 0302-9743 Series E-ISSN 1611-3349
issn_series 0302-9743
copyrightSpringer-Verlag Berlin Heidelberg 2003
The information of publication is updating

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A Comparison of Methods for Assessing the Structural Similarity of Proteins,tical analyses can then be performed on similarity scores for a set of proteins, to obtain a plot of ‘protein structure space’ [7]. Before such analyses are done however, one must be sure that the metric used accurately represents similarity.
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Self-consistent Knowledge-Based Approach to Protein Design,no acid sequences folding into a pre-assigned native conformation. This last issue, having obvious practical and evolutionary significance, has attracted considerable attention and effort of experimentalists and theorists [2, 3, 4, 5, 6, 7, 8].
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0302-9743 rkshopwhichwasorganizedandheldwith thegoaloftakinga snapshotofadiscipline undertumultuous growth. Indeed, the area of protein folding, docking and alignment is developing in response to needs for a mix of heterogeneous expertise spanning biology, chemistry, mathematics, computer science, and statist
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https://doi.org/10.1007/b11686algorithms; calculus; computational biology; computational molecular biology; data analysis; genome; neura
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