| 書目名稱 | Label-Free Biosensor Methods in Drug Discovery | | 編輯 | Ye Fang | | 視頻video | http://file.papertrans.cn/581/580233/580233.mp4 | | 概述 | Assists academic and industrial researchers involved in drug and probe discovery to adopt label-free techniques.Provides fundamental and practical methods from expert researchers.Includes tips and key | | 叢書名稱 | Methods in Pharmacology and Toxicology | | 圖書封面 |  | | 描述 | .This volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but may introduce artifacts in assay results. Addressing several fundamental and practical aspects as to how to implement label-free methods in the drug discovery process, this book covers a wide range of topics, including binding kinetics determination, fragment screening, antibody epitope mapping, protein-protein interaction profiling and screening, receptor pathway deconvolution, drug pharmacology profiling and screening, target identification, drug toxicity assessment, and physical phenotype profiling and diagnostics based on various cellular processes such as cell adhesion, migration, invasion, infection, and inflammation. As part of the .Methods in Pharmacology and Toxicology. series, chapters aim to provide key detail and implementation advice to aid with progress in the lab..Practical and thorough, .Label-Free Biosensor Methods in Drug Discovery. provides a new avenue for rapid access to a focused collection of highly regarded contributions in the field.. | | 出版日期 | Book 2015 | | 關鍵詞 | Biotechnology; Cell signaling; Clinical diagnostics; Drug safety assessment; Drug screening and profilin | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-2617-6 | | isbn_softcover | 978-1-4939-4961-8 | | isbn_ebook | 978-1-4939-2617-6Series ISSN 1557-2153 Series E-ISSN 1940-6053 | | issn_series | 1557-2153 | | copyright | Springer Science+Business Media New York 2015 |
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