Titlebook: Jak-Stat Signaling : From Basics to Disease; Thomas Decker,Mathias Müller Book 2012 Springer-Verlag Wien 2012 Cell Differentiation.Hematop

Perennial長(zhǎng)期的

FAZE

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桉樹(shù)

inquisitive

Universal and Specific Functions of STAT3 in Solid Tumours,s. Moreover, STAT3 was recently shown to play unexpected roles in regulating cell metabolism and mitochondrial activity via both transcriptional and non-transcriptional mechanisms. Here, we review the main knowledge about the role of STAT3 in solid tumours, with a particular focus on breast cancer and our recent work with mouse models.

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露天歷史劇

The Continuing Fascination with Jaks and Stats: An Introduction,ge Stark were fascinated by the fact that gene transcription could be induced within minutes after treating cells with type I interferons (IFN-I). The speed with which a signal generated by the plasma membrane–associated IFN-I receptor travelled to nuclear target genes suggested few intermediate ste

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Regulation of JAKs: Insights Gleaned from the Functional Protein Domains, 15 years until a first crystal structure of a Janus kinase domain was described and by today the structures of all four kinase domains have been explored. In this chapter we discuss the effects of the different JAK domains on the activity, trafficking and localisation of JAKs that were reported in

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馬賽克