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Titlebook: Intracellular Traffic and Neurodegenerative Disorders; Peter H. St. George-Hyslop,William C. C. Mobley,Yv Book 2009 Springer-Verlag Berlin

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發(fā)表于 2025-3-21 17:37:58 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Intracellular Traffic and Neurodegenerative Disorders
編輯Peter H. St. George-Hyslop,William C. C. Mobley,Yv
視頻videohttp://file.papertrans.cn/474/473135/473135.mp4
叢書名稱Research and Perspectives in Alzheimer‘s Disease
圖書封面Titlebook: Intracellular Traffic and Neurodegenerative Disorders;  Peter H. St. George-Hyslop,William C. C. Mobley,Yv Book 2009 Springer-Verlag Berlin
描述.This book explores the role of sub-cellular trafficking in the pathogenesis, treatment and prevention of neurodegenerative diseases. Recent findings point to faulty trafficking as contributing to the dysfunction and degeneration of neurons and neural circuits. Increasingly, research is targeting the mechanisms responsible and means to address them therapeutically. Many adult onset neurodegenerative diseases appear to arise from the accumulation of misfolded, neurotoxic peptides. This book investigates the ways in which sub-cellular trafficking pathways play a role both in the pathological accumulation of these misfolded proteins and in attempts to clear them. Because subcellular protein trafficking has an important role in the biology of neuronal function and survival, this also addresses how trophic factors maintain cell: cell interactions and how the underlying mechanisms may be compromised in neurodegenerative diseases. Examples where the use of such trophic factors may provide a way to modify neurodegenerative diseases are investigated..
出版日期Book 2009
關(guān)鍵詞Alzheimer; Alzheimer‘s disease; Huntingdon‘s disease; amyloid precursor protein; axonal transport; intram
版次1
doihttps://doi.org/10.1007/978-3-540-87941-1
isbn_softcover978-3-642-09972-4
isbn_ebook978-3-540-87941-1Series ISSN 0945-6066 Series E-ISSN 2196-310X
issn_series 0945-6066
copyrightSpringer-Verlag Berlin Heidelberg 2009
The information of publication is updating

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Intracellular Traffic and Neurodegenerative Disorders978-3-540-87941-1Series ISSN 0945-6066 Series E-ISSN 2196-310X
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發(fā)表于 2025-3-22 07:46:17 | 只看該作者
Research and Perspectives in Alzheimer‘s Diseasehttp://image.papertrans.cn/i/image/473135.jpg
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,Membrane Trafficking and Targeting in Alzheimer’s Disease, and hence are subjected to regulation by the lipid environment and membrane trafficking. This review focuses on how membrane-associated events regulate amyloidogenic processing of APP and discusses ways to design membrane trafficking-based strategies to interfere with the process.
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發(fā)表于 2025-3-22 16:44:36 | 只看該作者
Book 2009point to faulty trafficking as contributing to the dysfunction and degeneration of neurons and neural circuits. Increasingly, research is targeting the mechanisms responsible and means to address them therapeutically. Many adult onset neurodegenerative diseases appear to arise from the accumulation
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0945-6066 findings point to faulty trafficking as contributing to the dysfunction and degeneration of neurons and neural circuits. Increasingly, research is targeting the mechanisms responsible and means to address them therapeutically. Many adult onset neurodegenerative diseases appear to arise from the acc
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.Includes supplementary material: Mformation about a material can be gathered from its interaction with electromagnetic waves. The information may be stored in the amplitude, the phase, the polarisation, the angular distribution of energy transportation or the spectral characteristics. When re- trie
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