Titlebook: Innate DNA and RNA Recognition; Methods and Protocol Hans-Joachim Anders,Adriana Migliorini Book 2014 Springer Science+Business Media New Y

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Crystallization of Mouse RIG-I ATPase Domain: In Situ Proteolysisces an active signaling conformation. However, the details of this conformational change remain elusive until high-resolution crystal structures of different functional conformations are available. X-ray crystallography is a powerful tool to study structure–function relationships, but crystallizatio

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enormous

Structure Modeling of Toll-Like Receptorsissemination and for the development of acquired immunity. To understand how these receptors work, it is crucial to investigate them from a structural perspective. High-throughput genome sequencing projects have led to the identification of more than 3,000 TLR sequences. However, only several struct

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Analysis of Nucleic Acid-Induced Nonimmune Cell Death In Vitroattern recognition receptors by foreign nucleic acid promotes production of inflammatory cytokines (mostly type I IFNs) and at the later stage leads to cell death. Here, we describe reliable and simple methods to quantify cell death caused by nucleic acid recognition. Additionally, we report two dif

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