找回密碼
 To register

QQ登錄

只需一步,快速開始

掃一掃,訪問微社區(qū)

打印 上一主題 下一主題

Titlebook: Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog; Bruce Beutler Book 2008 The Editor(s

[復(fù)制鏈接]
查看: 18432|回復(fù): 44
樓主
發(fā)表于 2025-3-21 18:49:20 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog
編輯Bruce Beutler
視頻videohttp://file.papertrans.cn/463/462253/462253.mp4
叢書名稱Current Topics in Microbiology and Immunology
圖書封面Titlebook: Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog;  Bruce Beutler Book 2008 The Editor(s
描述This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists. They may hold the opinion that genetics has run its course since Mendel read his paper on peas in 1865. “Why bother with classical genetics,” they may ask. “Won’t all genes be knocked out soon anyway?” Or they are intimidated by genetics, with its heavy reliance on model organisms that seem so alien. “What has C. elegans to do with me?” the questioning might go. “It doesn’t even have lymphocytes. ” Such skeptics may be unaware that the mouse is fast becoming as tractable a model organism as the fly, and that humans may not be too far behind. So I would like to introduce the topic with a few words about the power of genetics, and why it has contributed so much to immunology, and to bi- ogy in general. Genetics, as the word is used here, is not merely th
出版日期Book 2008
關(guān)鍵詞asthma; autoimmune disease; autoinflammatory syndrome; autosomal recessive genodermatosis; bronchial ast
版次1
doihttps://doi.org/10.1007/978-3-540-75203-5
isbn_softcover978-3-642-09445-3
isbn_ebook978-3-540-75203-5Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog影響因子(影響力)




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog影響因子(影響力)學(xué)科排名




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog網(wǎng)絡(luò)公開度




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog被引頻次




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog被引頻次學(xué)科排名




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog年度引用




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog年度引用學(xué)科排名




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog讀者反饋




書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog讀者反饋學(xué)科排名




單選投票, 共有 0 人參與投票
 

0票 0%

Perfect with Aesthetics

 

0票 0%

Better Implies Difficulty

 

0票 0%

Good and Satisfactory

 

0票 0%

Adverse Performance

 

0票 0%

Disdainful Garbage

您所在的用戶組沒有投票權(quán)限
沙發(fā)
發(fā)表于 2025-3-21 21:32:16 | 只看該作者
板凳
發(fā)表于 2025-3-22 01:05:38 | 只看該作者
Host Defenses Against Human Papillomaviruses: Lessons from Epidermodysplasia Verruciformis thus represent a primary deficiency in intrinsic, constitutive immunity to betapapillomaviruses, or constitute a primary deficiency in innate immunity (or both). Keratinocytes, the home cells of HPVs, are likely to play a central role in both cases. An important issue is to establish which cellular
地板
發(fā)表于 2025-3-22 07:32:05 | 只看該作者
Innate Resistance to Flavivirus Infections and the Functions of 2′-5′ Oligoadenylate Synthetases some other diseases such as type 1 diabetes and multiple sclerosis. Finally, convergent observations indicate that the molecules encoded by the . cluster might be involved in other fundamental cellular functions such as cell growth and differentiation, gene regulation, and apoptosis.
5#
發(fā)表于 2025-3-22 10:31:16 | 只看該作者
Genetic Dissection of Host Resistance to ,: The , Locus and the , Genemosome 1 and shown to be especially important for control of pulmonary tuberculosis. Rampant progression of tuberculosis infection in the lungs of the .-susceptible mouse was associated with the development of necrotic lung lesions, which was prevented by the .-resistant allele. Using a positional c
6#
發(fā)表于 2025-3-22 13:33:22 | 只看該作者
, the , Locus, and the Molecular Basis of Peripheral Tolerancemmune responses. Furthermore, although mutations in the orthologous human gene result in a virtually identical phenotype to that seen in the mouse, it is unlikely that studying the human disease populations alone would have successfully identified this gene. Thus, despite the complete sequencing of
7#
發(fā)表于 2025-3-22 18:59:22 | 只看該作者
Fevers, Genes, and Innate Immunityme,” resulting in caspase-1 activation and subsequent release of the active proinflammatory cytokine interleukin-1β (IL-1β). The role of an established biochemical pathway in regulating inflammation was uncovered by the discovery that the hyperimmunoglobulin D with periodic fever syndrome (HIDS) res
8#
發(fā)表于 2025-3-22 23:06:18 | 只看該作者
9#
發(fā)表于 2025-3-23 01:23:05 | 只看該作者
10#
發(fā)表于 2025-3-23 07:57:08 | 只看該作者
 關(guān)于派博傳思  派博傳思旗下網(wǎng)站  友情鏈接
派博傳思介紹 公司地理位置 論文服務(wù)流程 影響因子官網(wǎng) 吾愛論文網(wǎng) 大講堂 北京大學(xué) Oxford Uni. Harvard Uni.
發(fā)展歷史沿革 期刊點(diǎn)評(píng) 投稿經(jīng)驗(yàn)總結(jié) SCIENCEGARD IMPACTFACTOR 派博系數(shù) 清華大學(xué) Yale Uni. Stanford Uni.
QQ|Archiver|手機(jī)版|小黑屋| 派博傳思國際 ( 京公網(wǎng)安備110108008328) GMT+8, 2026-1-20 05:48
Copyright © 2001-2015 派博傳思   京公網(wǎng)安備110108008328 版權(quán)所有 All rights reserved
快速回復(fù) 返回頂部 返回列表
南投市| 孝义市| 余姚市| 纳雍县| 获嘉县| 瓦房店市| 辽中县| 娄烦县| 贵定县| 随州市| 德惠市| 华蓥市| 阿坝| 卫辉市| 平远县| 阳高县| 雷州市| 甘孜| 车险| 双辽市| 昌乐县| 天全县| 曲麻莱县| 通州市| 惠东县| 肇庆市| 同德县| 土默特左旗| 兴宁市| 黑水县| 博乐市| 收藏| 年辖:市辖区| 濉溪县| 舞钢市| 什邡市| 滦平县| 翼城县| 盖州市| 江陵县| 黑水县|