Titlebook: Hydrogen Sulfide in Kidney Diseases; A Novel Pharmacother George J. Dugbartey,Alp Sener Book 2023 The Editor(s) (if applicable) and The Aut

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Hydrogen Sulfide and the Renal System,udies have demonstrated that at low micromolar concentrations, H.S plays a complex and essential role in normal renal function, and dysregulation of its production has been implicated in various renal pathologies. In addition, exogenous H.S administration has been reported to exhibit important thera

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Hydrogen Sulfide for Diabetic Kidney Disease and Focal Segmental Glomerulosclerosis, cytokines, activation of fibroblasts and renin-angiotensin-aldosterone system, and depletion of adenosine triphosphate. Moreover, existing therapies only retard the disease progression but do not prevent or reverse it. Therefore, novel modes of pharmacotherapeutic intervention are in demand to targ

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Hydrogen Sulfide for the Treatment of Hypertensive Nephropathy and Calcium-Based Nephrolithiasis,n monoxide, has been recognized and established to possess antihypertensive and renoprotective properties, which may represent an important therapeutic alternative for hypertensive nephropathy. In this chapter, recent findings from preclinical studies about the therapeutic effect of H.S against hype

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Hydrogen Sulfide as a Potential Therapy for COVID-19-Associated Nephropathy,ulfide (H.S), the third established member of gasotransmitter family, is emerging as a potential candidate, possessing important therapeutic properties including antiviral, anti-inflammatory, antithrombotic, and antioxidant properties. A recent clinical study revealed higher serum H.S levels in surv

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Hydrogen Sulfide for Prevention of Obstructive Nephropathy,l anti-inflammatory medications, opioids, and alpha-receptor blockers. However, there is no evidence that they mitigate renal injury. Therefore, identifying potential therapies that could be administered during obstruction may help to improve renal function following decompression. Scientific eviden

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Hydrogen Sulfide Against Ischemia-Reperfusion Injury in Transplantation of Kidney and Other Transpllation. Our findings in this chapter showed that storage of renal graft and other solid organ grafts in H.S-supplemented preservation solution or administration of H.S to organ donor prior to organ procurement and to recipient at the start and during reperfusion is a novel, simple, and cost-effectiv

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nt feature, which is used as the optimal feature subset to train SVM classifier. Finally, the feature subset with the highest SVM classification accuracy was regarded as optimal feature subset. The experimental results on 11 UCI datasets, a real clinical data sets and a gene expression dataset show