Titlebook: Human Blood Groups; Chemical and Biochem Helmut Schenkel-Brunner Book 2000Latest edition Springer-Verlag Wien 2000 Allele.Antigen.biochemis

Atmosphere

Kell System, erythrocytes is controlled by two proteins encoded by two independent genes: the . antigens . are produced by alleles of an autosomal gene, ., which has been located on chromosome 7 at position q33-35 distal to the cystic fibrosis locus [.,.,.,.]. The expression of the . antigens on the red cell is

武器

appall

Glycoconjugates,ific protein or oligosaccharide structures. But whereas proteins are usually thoroughly discussed in chemistry and biochemistry courses, carbohydrates and glycoconjugates are only briefly (and it seems reluctantly) mentioned. A brief survey of the structures and properties of this substance class is therefore appropriate.

聯(lián)邦

Biosynthesis of Glycoconjugates,l not be discussed in this book. Little attention is paid, however, to the biosynthesis of glyco- conjugates. Since these substances are of pivotal importance for blood group serology, the formation of glycoconjugates will be discussed below in detail.

HARD

Definitive

Spinal-Tap

Lewis System and Antigens Lex and Ley,’ in 1939 (see Race and S?nger [.]). Since that time further characters of the blood group . system have been defined — .{b} [.], .. [.], .. [.], and the embryonal Lewis antigen, .. (originally termed ..) [.]..

雇傭兵

P System,gens . [.] and .. [.,.,.] were discovered and identified as belonging to the . system. Five blood group . phenotypes can be defined according to the presence or absence of these three serological specificities on the erythrocytes, two of which, .., and .., are frequent and three, ..,.. and ., very rare (. and .) [.]:

反復(fù)拉緊

色情

Polyagglutination,human adults, independent of standard blood groups [.,.]. This unusual reactivity is due to the fact that antibodies normally present in human sera bind to secondarily altered erythrocyte membrane antigens.