Titlebook: Hemostasis and Thrombosis; Methods and Protocol Emmanuel J. Favaloro,Robert C. Gosselin Book 2023Latest edition The Editor(s) (if applicabl

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Harmonization of Hemostasis Testing Across a Large Laboratory Network: An Example from Australiaion/standardization provides a common platform for test procedures and documentation across different laboratories. This enables staff to be deployed across several laboratories, if required, without additional training, since test procedures and documentation are the “same” in the different laborat

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Protocols for D-Dimer Measurements for Aid to Diagnosis or Exclusion of Venous Thromboembolism(1) as aid to diagnosis of various conditions and (2) venous thromboembolism (VTE) exclusion. If the manufacturer cites a VTE exclusion claim, the D-dimer test must only be used in evaluating patients with a non-high or unlikely pretest probability for pulmonary embolism and deep vein thrombosis. D-

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Evaluation of Activated Protein C Resistance Using Thrombin Generation Test) V has at first permitted the description of this phenotypic pattern and corresponded to a transition (guanine to adenine) at nucleotide 1691 in the gene coding for factor V, resulting in the replacement of arginine at position 506 by a glutamine. This confers to this mutated FV a resistance toward

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Performance of Chromogenic Protein C (PC) Testingon with the thrombin-thrombomodulin complex, PC is converted to its active form, activated PC (APC). APC complexes with protein S and regulates thrombin generation by the inactivation of Factors Va and VIIIa. The role of PC as a key regulator of the coagulation process is highlighted in the deficien

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