Titlebook: Handbook of Antimicrobial Resistance; Matthias Gotte,Albert Berghuis,Donald Sheppard Living reference work 20200th edition

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https://doi.org/10.1057/9781137292148 is unique among HIV antiretrovirals as it encompasses drugs that target the different stages of the HIV entry cascade. There are currently 2 FDA-approved drugs in this class, the chemokine receptor-5 (CCR5) antagonist maraviroc (MVC) and the fusion inhibitor enfuvirtide (T-20). Attachment inhibitor

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Kevin Buterbaugh,Richard FultonV infection, allowing for viral elimination in the majority of treated patients. The first two drugs to be approved for the treatment of HCV genotype 1 infection were the HCV NS3/4A protease inhibitors telaprevir and boceprevir. However, their administration in combination with pegylated interferon

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Food Security and Agriculture Sector, features of RNA viral quasispecies such as internal interactions within mutant spectra and the effect of population size and bottleneck events as they affect the frequency of inhibitor-escape mutants. Genetic barriers to resistance and fitness cost of specific amino acid substitutions involved in r

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