Titlebook: Germinal Centers; Methods and Protocol Dinis Pedro Calado Book 2017 Springer Science+Business Media LLC 2017 GCs.Antibody immune responses.

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Development of Mouse Model Systems of Germinal Center Lymphomas,omplexity of these mouse models. Thus, bone marrow (BM)-derived chimerism is an attractive approach to study GC B cell derived lymphomagenesis, as it allows for an efficient allocation of resources and reduces the number of animals used.

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https://doi.org/10.1007/978-3-031-38801-9s that exhibit GC B cell-like phenotype and acquire abilities to differentiate into memory B cells or bone marrow plasma cells depending on cytokine conditions. This system will allow us to elucidate the molecular mechanisms of GC B cell differentiation.

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