Titlebook: Genomic Instability and Cancer Metastasis; Mechanisms, Emerging Chris Maxwell,Cal Roskelley Book 2015 Springer International Publishing Swi

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,Nanomedicine—Nanoparticles in Cancer Imaging and Therapy,nanotechnology is a quickly evolving field of interdisciplinary research that involves the biomedical application of nanoparticles, which are nanoscale devices that are able to overcome biological barriers, specifically recognize a single type of cancer cell, and accumulate preferentially in tumors.

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The Generation, Detection, and Prevention of Genomic Instability During Cancer Progression and Metaffers selective advantages to the tumor, the tumor-specific loss of these pathways may provide therapeutic opportunities, which could be personalized through knowledge of the specific types of genomic instability that characterize an individual’s tumor.

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Animal Models of Metastasis,to study mechanisms underlying metastatic tumour cell dissemination. We then discuss selected genetically engineered mouse models of metastatic cancer, which are powerful tools to elucidate the oncogenic potential of genes of interest. Murine tumour xenografts are also considered as the traditional

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,Nanomedicine—Nanoparticles in Cancer Imaging and Therapy,rugs can be integrated into their design for more efficient imaging and treatment of the tumor with fewer side effects. Recent advances in nanomedicine raise exciting possibilities for future nanoparticle applications in personalized cancer therapy.