| 書目名稱 | Genomic Instability and Cancer Metastasis |
| 副標(biāo)題 | Mechanisms, Emerging |
| 編輯 | Chris Maxwell,Cal Roskelley |
| 視頻video | http://file.papertrans.cn/383/382898/382898.mp4 |
| 概述 | Connects cancer metastasis with genomic instability in a comprehensive manner.Outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes.Reviews emerging themes and highl |
| 叢書名稱 | Cancer Metastasis - Biology and Treatment |
| 圖書封面 |  |
| 描述 | Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1?outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas. |
| 出版日期 | Book 2015 |
| 關(guān)鍵詞 | Cancer Metastasis; DNA damage response; Genomic instability; Therapeutic approaches; Tumor heterogeneity |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-12136-9 |
| isbn_softcover | 978-3-319-35295-4 |
| isbn_ebook | 978-3-319-12136-9Series ISSN 1568-2102 Series E-ISSN 2215-1648 |
| issn_series | 1568-2102 |
| copyright | Springer International Publishing Switzerland 2015 |
|Archiver|手機(jī)版|小黑屋|
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