Titlebook: GTPase Protocols; The Ras Superfamily Ed Manser,Thomas Leung Book 2002 Humana Press 2002

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ARF-Directed Guanine-Nucleotide-Exchange (GEP) Proteinstivating protein (GAP), which accelerates GTP hydrolysis. Activation of the inactive GDP-bound ARF requires the action of a guanine nucleotide-exchange protein or GEP, which accelerates the release of bound nucleotide via stabilization of the guanine nucleotide-free protein (.).

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Arf6 and its Role in Cytoskeletal ModulationR) and Golgi complex and in the maintenance of the organization of the Golgi complex (.). Arf1 serves this dual function through the modification of Golgi-membrane lipid composition and the assembly of cytosolic coat-protein complexes onto Golgi membranes.

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