Titlebook: Extrasynaptic GABAA Receptors; Adam C. Errington,Giuseppe Di Giovanni,Vincenzo Cr Book 2014 Springer Science+Business Media, LLC 2014 GABA

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Book 2014evant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.

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Extrasynaptic GABAA Receptors and Tonic Inhibition in Spinal Cord,h motor control, chronic pain and anesthesia. This chapter highlights past and present developments in the field of extrasynaptic GABA. receptors and emphasizes their subunit composition, distribution, and physiological role in the spinal cord.

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The Role of Peri-synaptic GABA Receptors After Stroke,process in these events is alteration in neuronal response to incoming inputs—manipulations that increase neuronal firing to a given input are likely to induce changes in neuronal structure and alterations in cortical maps. It has been assumed that changes in neuronal excitability underlie processes

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The Role of Extrasynaptic GABAA Receptors in Focal Epilepsy,ence for such a change in GABA. receptor-mediated inhibition during epileptogenesis and speculate on the possible functional impact that such a shift in inhibition will have. In particular, we argue that shifts from phasic to tonic inhibition in the hippocampus will lead to a maintenance of “inhibit

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,GABAergic Control of the Hypothalamic–Pituitary–Adrenal (HPA) Axis: Role of Extrasynaptic GABAA RecGABA.Rs, respectively. The GABAergic control of the HPA axis is highly plastic and is altered by both acute and chronic stress. Here, I review the role of extrasynaptic GABA.Rs in the regulation of the HPA axis and the physiological response to stress.

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