Titlebook: Exploring Protein Structure: Principles and Practice; Tim Skern Textbook 2018 Springer International Publishing AG, part of Springer Natur

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Exploring Fundamentals,cids in proteins, with an emphasis on hydrogen bonding, ionization, and van der Waals forces. Hydrogen bonds will be illustrated using the structure of tyrosyl-tRNA synthetase, one of the first enzymes specifically modified by mutagenesis to investigate the importance of such bonds in enzymatic catalysis.

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Textbook 2018cture databases. Readers will find easily understandable, step-by step exercises and video-trainings to support them in grasping the fundamental concepts..After reading this book, readers will have the skills required to independently explore and analyze macromolecular structures, will be versed in

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https://doi.org/10.1007/978-3-319-93970-4chapter will also introduce the various types of turns that link the secondary structure elements together and show how the turns can be characterized by their torsion angles and hydrogen-bonding properties. A discussion of preferences of the amino acids to be found in α-helices, β-sheets, or turns will round off the chapter.

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Hollyweird Science: The Next Generationing another β-fold, known as the jelly roll, frequently found in the particles of icosahedral viruses. Using simple PyMOL commands, the entire shell of an icosahedral virus is assembled. Together, all of the examples show that similar folds involving β-sheets can be constructed by proteins with completely unrelated primary sequences (? Table 8.1).

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