Titlebook: Epigenetic Mechanisms in Cellular Reprogramming; Alexander Meissner,J?rn Walter Book 2015 Springer-Verlag Berlin Heidelberg 2015 DNA methy

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Histone Variants and Reprogramming in Early Development,ts natural context, where this process occurs with a high efficiency to give rise to a new developmental programme, will help us to understand how we can modulate cell plasticity in induced and experimental models. Although there is still much to learn on how specific histone variants regulate repro

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Epigenetic Regulation of Pluripotency by Polycomb Group Proteins,etic changes happening during differentiation induction that are crucial for lineage specification. The Polycomb group of genes codes for a variety of proteins that maintain repressive chromatin states. They are part of a complex cellular memory system that creates a layer of epigenetic information

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Stella and Zygotic Reprogramming,mbryo, the parental genomes undergo extensive epigenetic reprogramming, including genome-wide DNA demethylation. Shortly after fertilization, DNA methylation of the paternal genome is rapidly removed by a replication-independent process. In contrast, DNA methylation of the maternal genome is reduced

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PRC1-Mediated Gene Silencing in Pluripotent ES Cells: Function and Evolution,ifferentiate into all cell lineages of an organism (cell types of the three embryonic germ layers, i.e., ecto-, endo-, and mesoderm, and the germ cell lineage) and to generate pluripotent daughter cells. It seems obvious that these special features of pluripotent cells must be reflected in molecular

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