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Titlebook: Epigenetic Mechanisms in Cellular Reprogramming; Alexander Meissner,J?rn Walter Book 2015 Springer-Verlag Berlin Heidelberg 2015 DNA methy

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書(shū)目名稱Epigenetic Mechanisms in Cellular Reprogramming
編輯Alexander Meissner,J?rn Walter
視頻videohttp://file.papertrans.cn/314/313218/313218.mp4
概述Contains translational medicine aspects such as B cell programming and reprogramming in cancer.Includes extensive glossary.Understanding stem cell formation is key to develop novel drugs
叢書(shū)名稱Epigenetics and Human Health
圖書(shū)封面Titlebook: Epigenetic Mechanisms in Cellular Reprogramming; Alexander Meissner,J?rn Walter Book 2015 Springer-Verlag Berlin Heidelberg 2015 DNA methy
描述.The ability of a single genome to give rise to hundreds of functionally distinct cell type programs is in itself remarkable. Pioneering studies over the past few decades have demonstrated that this plasticity is retained throughout development, a phenomenon of epigenetic programming and reprogramming that remains one of the most fascinating areas of modern biology, with major relevance to human health and disease. This book presents the basic biology involved, including key mechanistic insights into this rapidly growing field..
出版日期Book 2015
關(guān)鍵詞DNA methylation; X-chromosome silencing; germline development; reprogramming; small RNAs; sperm epigenome
版次1
doihttps://doi.org/10.1007/978-3-642-31974-7
isbn_softcover978-3-662-51062-9
isbn_ebook978-3-642-31974-7Series ISSN 2191-2262 Series E-ISSN 2191-2270
issn_series 2191-2262
copyrightSpringer-Verlag Berlin Heidelberg 2015
The information of publication is updating

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https://doi.org/10.1007/978-1-4757-2774-6cations at later developmental stages. In this chapter we will discuss the major molecular differences occurring during the first phase of epigenetic reprogramming with a focus on DNA modification dynamics in the mammalian zygote.
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Sauerstoff-Mehrschritt-Therapiecomplexes (PRCs) are key epigenetic regulators of development and cell specification. Here we summarize and discuss recent data on the role of PRC1 for the establishment and maintenance of embryonic stem (ES) cell pluripotency with special emphasis on the evolution of mammalian orthologs of PRC1 components.
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Stella and Zygotic Reprogramming,“developmental pluripotency-associated 3”) is required for both the maintenance of DNA methylation status of some imprinted genes and retrotransposons and for the establishment of epigenetic asymmetry in zygotes.
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DNA Methylation Reprogramming in Preimplantation Development,cations at later developmental stages. In this chapter we will discuss the major molecular differences occurring during the first phase of epigenetic reprogramming with a focus on DNA modification dynamics in the mammalian zygote.
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PRC1-Mediated Gene Silencing in Pluripotent ES Cells: Function and Evolution,complexes (PRCs) are key epigenetic regulators of development and cell specification. Here we summarize and discuss recent data on the role of PRC1 for the establishment and maintenance of embryonic stem (ES) cell pluripotency with special emphasis on the evolution of mammalian orthologs of PRC1 components.
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