Titlebook: Engineering Translational Models of Lung Homeostasis and Disease; Chelsea M. Magin Book 2023 The Editor(s) (if applicable) and The Author(

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https://doi.org/10.1057/978-1-137-59445-72]. Whereas traditional reductionist approaches to in vitro models enable teasing apart the precise signaling pathways, cellular interactions, and response to biochemical and biophysical cues, model systems that incorporate higher complexity are needed to ask questions about physiology and morphogen

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Erich H. Loewy,Roberta Springer Loewypment, multipotent mesenchymal and epithelial progenitors drive the diversification of fates that results to the plethora of cell types that compose the airways and alveolar space of the adult lungs. Use of mouse genetic models, including lineage tracing and loss-of-function studies, has elucidated

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