Titlebook: Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery; Electrically Mediate Mark J. Jaroszeski,Richard Heller,Richard Gilb

Microaneurysm

GONG

Electrolysis

Aqueous-Humor

Electrochemotherapytating the delivery of a chemotherapeutic drug into tumor cells at concentrations that are sufficient for effective cell killing and, at the same time, to minimize the drug concentration in normal tissue.

adhesive

用手捏

Electroporation of Muscle Tissue In Vivo localized cancers, the question of normal tissue sensitivity to electroporation needs to be investigated. Finally, efficient in vivo gene transfection to muscle tissue by electroporation has recently been reported (.,.), warranting increased knowledge on in vivo electroporation of muscle tissue.

Engaged

Treatment of Rat Bladder Cancer With Electrochemotherapy In Vivoase in the concentration of Bleomycin, in bladder cancer cells in vitro and in normal bladder tissue of rats in vivo (.). Here we introduce our method to assess the effectiveness of this therapy for rat’s bladder cancer.

是貪求

In Vitro and Ex Vivo Gene Delivery to Cells by Electroporationthus comprises two steps. The first step is electroporation, which is governed by the electrical properties of the cell and the suspension medium. The controlling parameters are mainly electrical. The second step is recovery, which must take into account the biological characteristics of the cells. We consider these two steps in this chapter.

粗魯?shù)娜?/a>

Delivery of Genes In Vivo Using Pulsed Electric Fieldsdielectric breakdown of the membrane. This physical phenomenon was termed electroporation, or electropermeabilization, because it was observed that molecules that do not normally pass through the membrane gain intracellular access after the cells were treated with electric fields.

Panther

Book 2000iated delivery have tremendous potential for the treatment of human disease. For example, the ef- cient delivery of drugs and plasmid DNA has strong implications for improving standard therapies, as well as gene therapies. This potential was realized about 12 years ago when electric pulses were used