Titlebook: Drug Studies in the Elderly; Methodological Conce Neal R. Cutler (Director),Prem K. Narang (Supervis Book 1986 Plenum Publishing Corporatio

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Antiepileptic Drugs in the Elderlyeven a cerebrovascular accident, may not recur, the incidence and prevalence of chronic seizures (“epilepsy”) increase with aging. Hauser and Kurland found an overall epilepsy incidence rate for Rochester, Minnesota of 5.7/1000, but 10.2/1000 for the population over 60..

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G,te 15–17% of the total population. Given achievements and improvements in health care, the figure of 17% could climb as high as 25–30%. These projections are not influenced by changes in fertility rates. The older generation in 2030 will by and large be the baby boom population of the 1940s and 1950s grown older.

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M,even a cerebrovascular accident, may not recur, the incidence and prevalence of chronic seizures (“epilepsy”) increase with aging. Hauser and Kurland found an overall epilepsy incidence rate for Rochester, Minnesota of 5.7/1000, but 10.2/1000 for the population over 60..

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Cognitive Enhancers in Alzheimer’s Diseasec studies with these drugs have been few. Therefore, rather than choosing to discuss kinetics, as expected from the contributions in this part, we have decided to address methodological issues that pertain to all agents being evaluated in the elderly with some form of dementia.

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