Titlebook: Drug Studies in the Elderly; Methodological Conce Neal R. Cutler (Director),Prem K. Narang (Supervis Book 1986 Plenum Publishing Corporatio

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O,the elderly population with different types of dementia. It is important to clarify that the dose-response relationships with these agents in the elderly population are almost nonexistent. This difficulty associated with the clinical trials in dementia patients is primarily due to problems related t

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Epidemiology and Demography of Agingh rates have followed industrialization. Between 1880 and 1920 the impact of industrialization on demographic profiles was dramatically enhanced by a public health revolution, during which acute infectious diseases and tuberculosis became minor causes of death for the first time in history.

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Physiological Changes with Aginge of importance in influencing the design and conduct of drug studies. This will be done by briefly examining those physiological changes in humans that might be expected to influence disposition of and response to drugs. This approach is being taken for several reasons.

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Pharmacological Treatment of Parkinson’s Diseasene agonists; (4) monoamine oxidase inhibitors; (5) anticholinergic agents; and (6) amantadine. Levodopa is the cornerstone of Parkinsonism disease treatment. The other five drug classes are useful supplements or occasional alternatives to levodopa.

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